Jul 15, 2018 ... Ralph W. Ludwig Jr., a Frankfort, Kentucky (KY) Law Firm - Probate & Estate Administration. Ralph W. Ludwig Jr. - Frankfort, KY Updated: 07/15/2018 Your Profile? Update Now Ralph W Ludwig Jr. (Sole Practitioner) When viewing a listing, consider the state advertising restrictions to which lawyers and law firms must adhere, as well as our FindLaw.com Legal Directory disclaimer. Some lawyers publish comparative information regarding the services that they provide which may be subject to specific comparative communications restrictions. Comfort Level - Are you comfortable telling the lawyer personal information? Does the lawyer seem interested in solving your problem? Credentials - How long has the lawyer been in practice? Has the lawyer worked on other cases similar to yours? Cost - How are the lawyer's fees structured - hourly or flat fee? Can the lawyer estimate the cost of your case? City - Is the lawyer's office conveniently located? Not Sure What Questions To Ask A Lawyer? Here are a few to get you started: How long have you been in practice? How many cases like mine have you handled? How often do you settle cases out of court? Want To Check Lawyer Discipline? It is always a good idea to research your lawyer prior to hiring. Every state has a disciplinary organization that monitors attorneys, their licenses, and consumer complaints. By researching lawyer discipline you can: Ensure the attorney is currently licensed to practice in your state Gain an understanding of his or her historical disciplinary record, if any. Determine the seriousness of complaints/issues which could range from late bar fees to more serious issues requiring disciplinary action.
May 24, 1977 ... RALPH W. LUDWIG. FRANKFORT, KY. BILL GRAHAM,. FRANKFORT, KY. STEVEN B ... WILLIAM E McANULTY, JR. LOUISVILLE, KY. JEFFERSON. 13,043. 8,443. 20241010T173728Z-17d475c956f9dtzqvf5rycb47s0000000at00000000103eq
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Oct 11, 2020 ... ... Ludwig Jr., Ann Marie (Michael Hansen) Vogel, April Fraley and the late David Fraley Jr. Great grandma of Connor Vela, William Vela, Shianne ... May 28, 1939 - October 11, 2020
Jun 24, 2015 ... ... Ralph P Tufano , William H Westra , Chetan Bettegowda , Luis A Diaz Jr ... Ludwig Center for Cancer Genetics and Therapeutics, Howard ... An official website of the United States government Here's how you know Access keysNCBI HomepageMyNCBI HomepageMain ContentMain Navigation . 2015 Jun 24;7(293):293ra104. doi: 10.1126/scitranslmed.aaa8507. Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas Yuxuan Wang 1 , Simeon Springer 1 , Carolyn L Mulvey 2 , Natalie Silliman 1 , Joy Schaefer 1 , Mark Sausen 3 , Nathan James 1 , Eleni M Rettig 2 , Theresa Guo 2 , Curtis R Pickering 4 , Justin A Bishop 5 , Christine H Chung 6 , Joseph A Califano 7 , David W Eisele 2 , Carole Fakhry 7 , Christine G Gourin 2 , Patrick K Ha 7 , Hyunseok Kang 6 , Ana Kiess 8 , Wayne M Koch 2 , Jeffrey N Myers 4 , Harry Quon 8 , Jeremy D Richmon 2 , David Sidransky 2 , Ralph P Tufano 2 , William H Westra 5 , Chetan Bettegowda 9 , Luis A Diaz Jr 1 , Nickolas Papadopoulos 1 , Kenneth W Kinzler 1 , Bert Vogelstein 10 , Nishant Agrawal 11 DOI: 10.1126/scitranslmed.aaa8507 To explore the potential of tumor-specific DNA as a biomarker for head and neck squamous cell carcinomas (HNSCC), we queried DNA from saliva or plasma of 93 HNSCC patients. We searched for somatic mutations or human papillomavirus genes, collectively referred to as tumor DNA. When both plasma and saliva were tested, tumor DNA was detected in 96% of 47 patients. The fractions of patients with detectable tumor DNA in early- and late-stage disease were 100% (n = 10) and 95% (n = 37), respectively. When segregated by site, tumor DNA was detected in 100% (n = 15), 91% (n = 22), 100% (n = 7), and 100% (n = 3) of patients with tumors of the oral cavity, oropharynx, larynx, and hypopharynx, respectively. In saliva, tumor DNA was found in 100% of patients with oral cavity cancers and in 47 to 70% of patients with cancers of the other sites. In plasma, tumor DNA was found in 80% of patients with oral cavity cancers, and in 86 to 100% of patients with cancers of the other sites. Thus, saliva is preferentially enriched for tumor DNA from the oral cavity, whereas plasma is preferentially enriched for tumor DNA from the other sites. Tumor DNA in saliva was found postsurgically in three patients before clinical diagnosis of recurrence, but in none of the five patients without recurrence. Tumor DNA in the saliva and plasma appears to be a potentially valuable biomarker for detection of HNSCC.